Differential gene expression in SV40-med
β
Jose Pardinas; Zeng Pang; Jeanmarie Houghton; Vaseem Palejwala; Robert J. Donnel
π
Article
π
1997
π
John Wiley and Sons
π
English
β 234 KB
π 2 views
Normal human diploid fibroblasts (HF) have a limited life span, undergo senescence, and rarely, if ever, spontaneously immortalize in culture. Introduction of the gene for T antigen encoded by the DNA virus SV40 extends the life span of HF and increases the frequency of immortalization; however, imm