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Suzuki—Miyaura Cross-Coupling Reactions of Benzyl Halides with Potassium Aryltrifluoroborates.

✍ Scribed by Gary A. Molander; Maxwell D. Elia


Publisher
John Wiley and Sons
Year
2007
Weight
31 KB
Volume
38
Category
Article
ISSN
0931-7597

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Palladium-Catalyzed Carbonylative Suzuki
✍ Xiao-Feng Wu; Helfried Neumann; Matthias Beller 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 173 KB

## Abstract A general palladium‐catalyzed carbonylative cross‐coupling reaction of benzyl chlorides with potassium aryltrifluoroborates in water has been developed. Applying this improved methodology 16 different 1,2‐diarylethanones have been synthesized in 40–89% yield.