✦ LIBER ✦

Sustained Expression of Therapeutic Level of Factor IX in Hemophilia B Dogs by AAV-Mediated Gene Therapy in Liver

✍ Scribed by Wang, L

Book ID: 126597113
Publisher: Nature Publishing Group
Year: 2000
Tongue: English
Weight: 65 KB
Volume: 1
Category: Article
ISSN: 1525-0016
DOI: 10.1006/mthe.2000.0031

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Evidence of Multiyear Factor IX Expressi

Evidence of Multiyear Factor IX Expression by AAV-Mediated Gene Transfer to Skeletal Muscle in an Individual with Severe Hemophilia B

✍ JIANG, H; PIERCE, G; OZELO, M; DEPAULA, E; VARGAS, J; SMITH, P; SOMMER, J; LUK, 📂 Article 📅 2006 🏛 Nature Publishing Group 🌐 English ⚖ 242 KB

Intravenous administration of an AAV-2 v

Intravenous administration of an AAV-2 vector for the expression of factor IX in mice and a dog model of hemophilia B

✍ Harding, T C; Koprivnikar, K E; Tu, G H; Zayek, N; Lew, S; Subramanian, A; Sivak 📂 Article 📅 2004 🏛 Nature Publishing Group 🌐 English ⚖ 288 KB

Role of the vector genome and underlying

Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B

✍ Rogers, Geoffrey L; Martino, Ashley T; Zolotukhin, Irene; Ertl, Hildegund CJ; He 📂 Article 📅 2014 🏛 BioMed Central 🌐 English ⚖ 925 KB

Skeletal muscle-specific expression of h

Skeletal muscle-specific expression of human blood coagulation factor IX rescues factor IX deficiency mouse by AAV-mediated gene transfer

✍ Lihui Lai; Li Chen; Jianmin Wang; Hong Zhou; Daru Lu; Qi Wang; Xiaobo Gao; Xinfa 📂 Article 📅 1999 🏛 Science in China Press (SCP) 🌐 English ⚖ 473 KB

Sustained and therapeutic levels of huma

Sustained and therapeutic levels of human factor IX in hemophilia B mice implanted with microcapsules: key role of encapsulated cells

✍ Jianping Wen; Andrew Gómez Vargas; Frederick A. Ofosu; Gonzalo Hortelano 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 164 KB

## Abstract ## Background A gene therapy delivery system based on microcapsules enclosing recombinant cells engineered to secrete a therapeutic protein was explored in this study. In order to prevent immune rejection of the delivered cells, they were enclosed in non‐antigenic biocompatible alginat

A study of gene transfer and expression

A study of gene transfer and expression of human clotting factor IX in hemophilia B mice mediated by mini-adenoviral vector

✍ Xiaobo Gao; Chenbo Ye; Ding Shi; Li Chen; Xinfang Qiu; Jinglun Xue 📂 Article 📅 2003 🏛 Science in China Press (SCP) 🌐 English ⚖ 339 KB