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Sustained expression of Hif-1α in the diabetic environment promotes angiogenesis and cutaneous wound repair

✍ Scribed by Kimberly A. Mace; Diana H. Yu; Keyianoosh Z. Paydar; Nancy Boudreau; David M. Young

Book ID
109080479
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
432 KB
Volume
15
Category
Article
ISSN
1067-1927

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## Abstract Wound healing is impaired in elderly patients with diabetes mellitus. We hypothesized that age‐dependent impairment of cutaneous wound healing in __db__/__db__ diabetic mice: (a) would correlate with reduced expression of the transcription factor hypoxia‐inducible factor 1α (HIF‐1α) as