𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Inhibition of the VEGF expression and cell growth in hepatocellular carcinoma by blocking HIF-1α and Smad3 binding site in VEGF promoter

✍ Scribed by Ding Lei; Chen Xiaoping; Jing Kai; Wang Haiping; Zhang Wanguang

Publisher
Springer-Verlag
Year
2006
Tongue
Chinese
Weight
664 KB
Volume
26
Category
Article
ISSN
0510-9752

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Inhibition of HIF-1 alpha and VEGF expre
Inhibition of HIF-1 alpha and VEGF expression by the chemopreventive bioflavonoid apigenin is accompanied by Akt inhibition in human prostate carcinoma PC3-M cells
✍ Salida Mirzoeva; Nam Deuk Kim; Karen Chiu; Carrie A. Franzen; Raymond C. Bergan; 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 259 KB

## Abstract Progression of cancer leads to hypoxic solid tumors that mount specific cell signaling responses to low oxygen conditions. An important objective of anti‐cancer therapy is the development of new drugs that suppress hypoxic responses in solid tumors. Apigenin is a natural flavone that ha

Cyclic strain influences the expression
Cyclic strain influences the expression of the vascular endothelial growth factor (VEGF) and the hypoxia inducible factor 1 alpha (HIF-1α) in tendon fibroblasts
✍ Wolf Petersen; Deike Varoga; Thore Zantop; Joachim Hassenpflug; Rolf Mentlein; T 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 785 KB

## Abstract Neovascularization is involved in beneficial and detrimental processes of tendon pathology. We investigated the influence of repetitive motion on the expression of the most important angiogenic factor, the vascular endothelial growth factor (VEGF) in the 3T3 NIH fibroblast cell line an

Antiangiogenic activity of genistein in
Antiangiogenic activity of genistein in pancreatic carcinoma cells is mediated by the inhibition of hypoxia-inducible factor-1 and the down-regulation of VEGF gene expression
✍ Peter Büchler; Howard A. Reber; Markus W. Büchler; Helmut Friess; Robert S. Lave 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 281 KB 👁 2 views

## Abstract ## BACKGROUND Previous reports indicate that Genistein, a naturally occurring isoflavonoid, exhibits strong antiangiogenic activity. The underlying mechanism of inhibition, however, remains unclear. Among the biologic effects of Genistein are the inhibition of tyrosine kinases and the