The distribution, metabolism, and pharmacokinetics of physostigmine (Phy) and the time course of butyrylcholinesterase (BuChE) in plasma and cholinesterase (ChE) activity in brain and muscle and their relationship to Phy concentration were described after oral administration of 3H-Phy (650pg kg-') t
Sustained administration of the antidepressant venlafaxine in rats: pharmacokinetic and pharmacodynamic findings
โ Scribed by ; ; ; ; ; ;
- Publisher
- Springer-Verlag
- Year
- 2001
- Tongue
- English
- Weight
- 136 KB
- Volume
- 363
- Category
- Article
- ISSN
- 0028-1298
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
We studied the differences in pharmacokinetics and pharmacodynamics of the same dose of alendronate administered subcutaneously as intermittent bolus injection or continuous infusion in rats. Two rat models of bone disease were applied. Bone cancer was produced by intratibial inoculation of Walker c
The absorption, distribution, and excretion of bromocriptine were studied following oral and parenteral administration of non-radioactive and "C-labelled drug in the rat. Total radioactivity was measured in blood, tissues, and excreta by liquid scintillation counting while the parent drug was determ
To investigate the pharmacokinetics and the disposition of levoprotiline after i.v. and p.0. administration and to assess the absolute bioavailability, 12 healthy volunteers (1 1 women, 1 man) were given a 10 min i.v. infusion of 15 mg and a p.0. dose of 75 mg in a two-way crossover study. Blood and