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Susceptibility to urethane carcinogenesis of transgenic mice carrying a human prototype c-Ha-ras gene (rasH2 mice) and its modification by butylhydroxytoluene

โœ Scribed by Takashi Umemura; Yukio Kodama; Kyoji Hioki; Tohru Inoue; Tatsuji Nomura; Yuji Kurokawa


Book ID
117469596
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
106 KB
Volume
145
Category
Article
ISSN
0304-3835

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To determine if hemizygous transgenic mice carrying the human c-Ha-ras gene (CB6F1-Tg Hras2 mice (Hras2 mice)) are susceptible to the carcinogenic potential of known murine carcinogens, male and female Hras2 mice and their non-transgenic CB6F1 littermates (non-Tg mice) were each given a single intra