✦ LIBER ✦

Susceptibility to drug-induced apoptosis correlates with differential modulation of Bad, Bcl-2 and Bcl-xL protein levels

✍ Scribed by Tudor, G; Aguilera, A; Halverson, D O; Laing, N D; Sausville, E A

Book ID: 110016061
Publisher: Nature Publishing Group
Year: 2000
Tongue: English
Weight: 336 KB
Volume: 7
Category: Article
ISSN: 1350-9047
DOI: 10.1038/sj.cdd.4400688

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Retinamide-Induced Apoptosis in Glioblas

Retinamide-Induced Apoptosis in Glioblastomas is Associated with Down-Regulation of Bcl-xL and Bcl-2 Proteins

✍ Richard A. Lytle; Zhihong Jiang; Xiao Zheng; Ryuji Higashikubo; Keith M. Rich 📂 Article 📅 2005 🏛 Springer US 🌐 English ⚖ 363 KB

Heterogenous susceptibility to CD95-indu

Heterogenous susceptibility to CD95-induced apoptosis in melanoma cells correlates with bcl-2 and bcl-x expression and is sensitive to modulation by interferon-γ

✍ Selma Ugurel; Simone Seiter; Gunter Rappl; Alexandra Stark; Wolfgang Tilgen; Uwe 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 207 KB

The expression and functionality of the Fas receptor (CD95/APO-1) play an important role for the maintenance of tissue homeostasis. Various types of tumor cells have been shown to escape immune recognition by constitutive resistance to CD95-mediated apoptosis. Furthermore, several apoptosis-related

The spliced variant of hepatitis B virus

The spliced variant of hepatitis B virus protein, HBSP, interacts with Bcl-2/Bcl-xl in vitro and induces apoptosis in HepG2 cells

✍ Yi Wei Lu; Yu Dan Ren; Jing Bai; Wei Ning Chen 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 293 KB 👁 2 views

## Abstract We have recently reported that the naturally occurring spliced variant of Hepatitis B virus protein, HBSP, displayed proapoptotic activity through its BH3 domain. To investigate whether the BH3 domain in HBSP interacted with Bcl‐2 family of proteins, HBSP and Bcl‐2 family of proteins we

Characterization of vinblastine-induced

Characterization of vinblastine-induced Bcl-xL and Bcl-2 phosphorylation: evidence for a novel protein kinase and a coordinated phosphorylation/dephosphorylation cycle associated with apoptosis induction

✍ Du, Lihua; Lyle, Christopher S; Chambers, Timothy C 📂 Article 📅 2004 🏛 Nature Publishing Group 🌐 English ⚖ 343 KB

Mutation of p53 in head and neck squamou

Mutation of p53 in head and neck squamous cell carcinoma correlates with Bcl-2 expression and increased susceptibility to cisplatin-induced apoptosis

✍ Genevieve A. Andrews; Sichuan Xi; Rebecca G. Pomerantz; Charles J. Lin; William 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 515 KB

## Abstract ## Background. The p53 protein, a well‐known tumor suppressor that functions primarily as a transcription factor, initiates cell cycle arrest and apoptosis after genotoxic stress. The antiapoptotic regulator Bcl‐2 is a downstream modulator of p53‐induced apoptosis. Loss of function of

Suppression of nitric oxide–induced apop

Suppression of nitric oxide–induced apoptosis by N-acetyl-l-cysteine through modulation of glutathione, bcl-2, and bax protein levels

✍ Yuan-Soon Ho; Horng-Mo Lee; Tung-Chang Mou; Ying-Jan Wang; Jen-Kun Lin 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 264 KB

It has been demonstrated that nitric oxide (NO) can promote apoptosis in human cancer cells. To test the protective effects of antioxidants (N-acetyl-L-cysteine (LNAC)) and free-radical spin traps (5,5-dimethyl-1-pyrroline N-oxide and 2,2,6,6,-tetramethyl-1-piperidinyloxy) against NO-induced apoptos