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Susceptibility locus for non-syndromic cleft lip with or without cleft palate on chromosome 10q25 confers risk in Estonian patients

✍ Scribed by Tiit Nikopensius; Stefanie Birnbaum; Kerstin U. Ludwig; Triin Jagomägi; Mare Saag; Stefan Herms; Michael Knapp; Per Hoffmann; Markus M. Nöthen; Andres Metspalu; Elisabeth Mangold


Book ID
111756465
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
94 KB
Volume
118
Category
Article
ISSN
0909-8836

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Genetic risk factors for nonsyndromic cl
✍ Augusto Rojas-Martinez; Heiko Reutter; Oscar Chacon-Camacho; Rafael B. R. Leon-C 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 68 KB 👁 2 views

## Abstract **INTRODUCTION:** Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common of all birth defects. NSCL/P has a multifactorial etiology that includes both genetic and environmental factors. The __IRF6__ gene and three further susceptibility loci at 8q24, 10q2