Survival of pleomorphic sarcoma-37 transplanted virgin female DBA/2J mice: Effects produced by high blood glucose levels alone and in combination with drugs

Survival of pleomorphic sarcoma-37 trans

Survival of pleomorphic sarcoma-37 transplanted virgin female DBA/2J mice: Hyperthermia and hyperglycemia, alone and in combination with drugs

✍ Ronald E. Orth; Howard J. Swidler; Milo S. Zarakov 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 260 KB

Sarcoma-37 (S-37) transplanted DBA/2J mice were submitted to a controlled whole body hyperglycemic-hyperthermic ("double attack") treatment. A single exposure to the 3-hr 400-500-mg% blood glucose level coupled with 1 hr of whole body 40.0 degrees warming was safe and extended longevity by 40% over