Surgical pathologic spread patterns of endometrial cancer: A gynecologic oncology group study
β Scribed by William T. Creasman; C. Paul Morrow; Brian N. Bundy; Howard D. Homesley; James E. Graham; Paul B. Heller
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 624 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0008-543X
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β¦ Synopsis
The surgical pathologic features of 621 patients with Stage I carcinoma of the endometrium are presented. All patients were treated with primary surgery consisting of total abdominal hysterectomy, bilateral salpingo-oophorectomy, selective pelvic and paraaortic lymphadenectomy and peritoneal cytology. An appreciable number of patients (144-2296) with Stage I cancers have disease outside of the uterus (lymph node metastasis, adenexal disease, intraperitoneal spread and/or malignant cells in peritoneal washings). Multiple prognostic factors particularly grade and depth of invasion are related to extrauterine disease. This study adds credence to the primary surgical approach with individualized postoperative therapy as indicated.
π SIMILAR VOLUMES
Numerous pathologic factors have heen identified as important in predicting outcome for women with endometrial adenocarcinoma. However, most patients have a mixture of good and bad factors. For these women, the prognosis is uncertain, and it is often unclear whether postoperative therapy is indicate