Surface Modification of Polymeric Biomaterials

✍ Scribed by Buddy D. Ratner (auth.), Buddy D. Ratner, David G. Castner (eds.)

• Publisher: Springer US
• Year: 1997
• Tongue: English
• Leaves: 200
• Edition: 1
• Category: Library

✦ Synopsis

Applications of synthetic materials in medicine date back over 4000 year2. The Egyptians used linen as sutures. In the Roman Empire, gold was used in dentistry. Perhaps even earlier, ivory and bone may have been used in the body by practitioners of the healing arts. The historical origins of modem biomaterials science are also hard to precisely trace, but many of the ideas that define biomaterials as we know them today evolved in the late 1950s and early 1960s. Surface modification technology has played a prominent role in biomaterials science, and has paralleled the evolution of the modem field. In a symposium organized by the Artifical Heart Program of the NIH National Heart Institute and the Artificial Kidney program of the NIH National Institute of Arthritis and Metabolic Diseases, held in Atlantic City, New Jersey, in 1968, there were already a number of presentations on surface modification. Surface characterization at that time included scanning electron microscopy, ellipsometry, contact angle methods, and infrared internal reflection methods.

✦ Table of Contents

Front Matter....Pages i-viii
Surface Modification of Polymers for Biomedical Applications: Chemical, Biological, and Surface Analytical Challenges....Pages 1-9
A Creation of an Intelligent Surface — The Design of a Reactive Surface with Stimuli-Sensitivity toward Temperature and pH....Pages 11-19
In-Situ Surface Modification of Contact Lens Polymers....Pages 21-26
Surface Modification of Segmented Polyurethaneureas via Oligomeric End Groups Incorporated During Synthesis....Pages 27-33
XPS and SSIMS Characterization of Surfaces Modified by Plasma Deposited Oligo(Glyme) Films....Pages 35-44
Deposition of Fluorocarbon Films by Remote RF Glow Discharges....Pages 45-52
Plasma Copolymerization of Tetrafluoroethylene and Chlorotrifluoroethylene....Pages 53-60
Preparation of a Plasma Polymerized Tetramethylhydrocyclotetrasiloxane Membrane on Microporous Hollow Fibers....Pages 61-68
Plasma-Treatments of Polymers by NH 3 -H 2 RF Glow Discharges: Coupling Plasma and Surface Diagnostics....Pages 69-77
Surface Characterization of Fiber-Supported Hydrogels....Pages 79-87
XPS Analyses of Plasma-Treated Silicone Rubber....Pages 89-96
Assaying Primary Amines on Modified Polymer Surfaces Using TIRF Spectroscopy....Pages 97-105
Surface Tension Analysis of PBT and PET Fibres Based Leukodepletion Filters....Pages 107-115
The Self-Assembly and Inhibition of Protein Adsorption by Thiolated Dextran Monolayers at Hydrophobic Metal Surfaces....Pages 117-127
Hydrolysis of a Neutral Hydrogel and Biomolecule Attachment to Increase Cell Adhesion and Migration....Pages 129-134
Surface Attachment of Functional Peptides by Electrochemical Polymerisation....Pages 135-146
Covalently Attached Thin Coatings Comprising Saccharide and Alkylene Oxide Segments....Pages 147-156
Heparin Immobilization Onto Sol-Gel Derived Organic-Inorganic Hybrid Network....Pages 157-164
Covalent Surface Attachment of Polysaccharides via Bifunctional Epoxides....Pages 165-173
Thermal Recovery of Cells Cultured on Poly(N-Isopropylacrylamide) Surface-Grafted Polystyrene Dishes....Pages 175-181
Grafting of PEO via the Williamson Ether Synthesis onto Polymeric Surfaces and Their Affinity for Proteins....Pages 183-191
Four Protein-Friendly Approaches to Polymer Surface Metallization Using Monolayers of Gold Nanoparticles....Pages 193-201
Back Matter....Pages 203-206

✦ Subjects

Physical Chemistry