Surface Membrane Receptors: Interface Between Cells and Their Environment

✍ Scribed by S. J. Singer (auth.), Ralph A. Bradshaw, William A. Frazier, Ronald C. Merrell, David I. Gottlieb, Ruth A. Hogue-Angeletti (eds.)

• Publisher: Springer US
• Year: 1976
• Tongue: English
• Leaves: 480
• Series: NATO Advanced Study Institutes Series 11
• Edition: 1
• Category: Library

✦ Synopsis

The NATO Advanced Study Institute entitled "Surface Membrane Receptors: Interface Between Cells and Environment" was held in Bellagio, Italy September 13-21, 1975. This meeting was an attempt to bring together in an international and interdisci­ plinary forum scientists who are studying recognitive phenomona which take place at the surface membrane of cells. While an attempt was made to restrict the subject areas covered at the meeting to those experimental systems which have been biochemi­ cally characterized to some extent, it will also be noted that some contributions to this volume represent a preliminary iden­ tification of interesting regulatory substances which might reasonably be expected to act at the cell surface. This book is divided into four sections reflecting the subject areas covered during the course of the meeting. The first section entitled "Membrane Structure and Receptor Function" is intended as an overview of the role of membrane structure in determining the regulatory properties, physical state, structure and location of cell surface receptors. It should be noted that the plasma membrane itself provided the unifying theme for the intention­ ally diverse contributions to this volume. The following three sections represent an arbitrary division into three levels of structural complexity of the things in their external environ­ ment with which cells must specifically interact.

✦ Table of Contents

Front Matter....Pages i-xi
Front Matter....Pages N1-N1
The Fluid Mosaic Model of Membrane Structure: Some Applications to Ligand-Receptor and Cell-Cell Interactions....Pages 1-24
Structure and Function of Membranes and the Role of the Plasma Membrane in Metabolic Regulations....Pages 25-38
Front Matter....Pages N3-N3
Cellular Recognition in Slime Molds: Evidence for its Mediation by Cell Surface Species-Specific Lectins and Complementary Oligosaccharides....Pages 39-55
Multiple Lectins in Two Species of Cellular Slime Molds....Pages 57-66
Receptors Mediating Cell Aggregation in Dictyostelium Discoideum ....Pages 67-72
Cell Surface Components Mediating the Reaggregation of Sponge Cells....Pages 73-86
Isolation of a Hansenula Wingei Mutant with an Altered Sexual Agglutinin....Pages 87-97
The Mating Phenomenon in Escherichia Coli ....Pages 99-108
Neuronal Cell Adhesion....Pages 109-131
Evidence for a Gradient of Adhesive Specificity in the Developing Chick Retina....Pages 133-145
Front Matter....Pages N5-N5
Membrane Receptors for Bacterial Toxins....Pages 147-167
Gangliosides as Possible Membrane Receptors for Cholera Toxin....Pages 169-178
Binding and Uptake of the Toxic Lectins Abrin and Ricin by Mammalian Cells....Pages 179-192
Studies on an Hepatic Membrane Receptor Specific for the Binding and Catabolism of Serum Glycoproteins....Pages 193-197
Concanavalin a Induced Changes of Membrane-Bound Lysolecithin Acyltransferase of Thymocytes....Pages 199-213
Cooperative Regulation of Hormone Binding Affinity for Cell Surface Receptors....Pages 215-226
Specific Interaction of Nerve Growth Factor with Receptors in the Central and Peripheral Nervous Systems....Pages 227-246
Studies on the Molecular Properties of Nerve Growth Factor and its Cellular Biosynthesis and Secretion....Pages 247-267
Specific Binding and Ability of Vasoactive Intestinal Octacosa-Peptide (VIP) to Activate Adenylate Cyclase in Isolated Pancreatic Acinar Cells from the Guinea Pig....Pages 269-289
α-Melanotropin Receptors: Non-Identical Hormonal Message Sequences (Active Sites) Triggering Receptors in Melanocytes, Adipoctytes and CNS Cells....Pages 291-304
Front Matter....Pages N5-N5
Endothelial Proliferation Factor....Pages 305-315
Evidence for a Macromolecular Effector of Cell Differentiation in Dictyostelium Discoideum Amoebae....Pages 317-327
Front Matter....Pages N7-N7
Conformational Changes of the Cholinergic Receptor Protein from Torpedo Marmorata as Revealed by Quinacrine Fluorescence....Pages 329-343
Cholinergic Sites in Skeletal Muscle....Pages 345-361
Appearance of Specialized Cell Membrane Components During Differentiation of Embryonic Skeletal Muscle Cells in Culture....Pages 363-375
Affinity Partitioning of Receptor-Rich Membrane Fractions and Their Purification....Pages 377-385
Biochemical and Molecular Characteristics of β-Adrenergic Receptor Binding Sites....Pages 387-404
Characterization of the β-Adrenergic Receptor and the Regulatory Control of Adenylate Cyclase....Pages 405-418
Chemotaxis in Bacteria....Pages 419-435
Cyclic AMP Receptors at the Surface of Aggregating Dictyostelium Discoideum Cells....Pages 437-442
Cyclic AMP Receptor Activity in Developing Cells of Dictyostelium Discoideum ....Pages 443-453
Prostaglandin F 2α Receptors in Corpora Lutea....Pages 455-472
Back Matter....Pages 473-482

✦ Subjects

Biochemistry, general