Sur l'aminolyse des amides. II. Action catalytique des acides

✍ Scribed by R. Jaunin; M. Beretta Piccoli; T. Charalambous

• Publisher: John Wiley and Sons
• Year: 1954
• Tongue: German
• Weight: 354 KB
• Volume: 37
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.19540370126

✦ Synopsis

Abstract

As an example of aminolysis of amides, the reaction between acetanilide and o‐anisidine has been studied with special reference to the catalytic action of acids. In the case of a weak acid, the rate of aminolysis increases continuously as the concentration of the catalyzing acid is increased; on the other hand, in the case of a strong acid, the rate passes through a maximum value. A mechanism for aminolysis of amides, consistent with these facts, is suggested.