Supramolecular assemblies of ruthenium complexes and porphyrins

✍ Scribed by Henrique E Toma; Koiti Araki

• Publisher: Elsevier Science
• Year: 2000
• Tongue: English
• Weight: 392 KB
• Volume: 196
• Category: Article
• ISSN: 0010-8545
• DOI: 10.1016/s0010-8545(99)00041-7

✦ Synopsis

The build-up of polymetallic supermolecules based on porphyrins and ruthenium bipyridine complexes has been pursued with great interest. A relevant series of symmetric polynuclear species has been obtained by attaching four [Ru II (bipy) 2 Cl] groups to the pyridyl substituents of meso-tetra(4-pyridyl)porphyrin and its metallated derivatives. These compounds display a rich electrochemistry and versatile catalytic and photochemical properties, associated with the ruthenium-bipyridine and metalloporphyrin complexes. The supermolecular species interact very strongly with DNA, yielding by irradiation with visible light, very efficient single-strand breaks and formation of 8-oxo-7,8-dihydroxo-2%-deoxyguanosine.