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Suppressor of cytokine signaling 3 negative regulation of signal transducer and activator of transcription 3 in platelet-derived growth factor-induced fibroblast migration

โœ Scribed by Hiroshi NAGAI; Sho TOKUMARU; Koji SAYAMA; Yuji SHIRAKATA; Yasushi HANAKAWA; Satoshi HIRAKAWA; Xiuju DAI; Mikiko TOHYAMA; Lujun YANG; Koji HASHIMOTO


Book ID
108576297
Publisher
John Wiley and Sons
Year
2007
Tongue
French
Weight
157 KB
Volume
34
Category
Article
ISSN
0385-2407

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Epigenetic regulation of signal transduc
โœ Sampa Ghoshal (Gupta); Heinz Baumann; Meir Wetzler ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 350 KB

We have demonstrated that constitutive signal transducer and activator of transcription (STAT) 3 activity, observed in approximately 50% of acute myeloid leukemia (AML) cases, is associated with adverse treatment outcome. Constitutive STAT3 activation may result from the expression of oncogenic prot