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Suppressive T cell activity in synovial fluid of patients with rheumatoid arthritis is induced by human and not bacterial 60 kDa heat-shock protein

✍ Scribed by J.A.G. van Roon; W. van Eden; F.P.J.G. Lafeber; J.W.J. Bijlsma


Book ID
108408949
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
184 KB
Volume
56
Category
Article
ISSN
0165-2478

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## Abstract Recent evidence has pointed to the mycobacterial 65‐kDa heat‐shock protein (hsp 65) as an antigen that may be important in the pathogenesis of rheumatoid arthritis (RA). Using limiting dilution analysis the frequency of purified protein derivative of tuberculin (PPD) and hsp 65‐responsi