Presumptive tumor suppressor genes may be localized to specific chromosomes by the procedure of microcell fusion, whereby individual chromosomes derived from normal human cells are introduced into tumor cells. Allelic loss on chromosome I 8 is commonly seen in endometrial carcinoma, and the DCC gene
Suppression of tumorigenicity in human colon carcinoma cells by introduction of normal chromosome 5 or 18
โ Scribed by Tanaka, Kiyoko; Oshimura, Mitsuo; Kikuchi, Rei; Seki, Madoka; Hayashi, Takako; Miyaki, Michiko
- Book ID
- 109767070
- Publisher
- Nature Publishing Group
- Year
- 1991
- Tongue
- English
- Weight
- 554 KB
- Volume
- 349
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/349340a0
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