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Suppression of Tumor Growth and Downregulation of Platelet-derived Endothelial Cell Growth Factor/Thymidine Phosphorylase in Tumor Cells by Angiogenesis Inhibitor TNP-470

✍ Scribed by Mori, Jun ;Haisa, Minoru ;Naomoto, Yoshio ;Takaoka, Munenori ;Kimura, Masashi ;Yamatsuji, Tomoki ;Notohara, Kenji ;Tanaka, Noriaki

Book ID
108581932
Publisher
Wiley (Blackwell Publishing)
Year
2000
Tongue
English
Weight
306 KB
Volume
91
Category
Article
ISSN
0910-5050

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## Abstract ## BACKGROUND Thymidine phosphorylase (TP) is identical to platelet‐derived endothelial cell growth factor (PDECGF) and has angiogenic activity. Little is known about the significance of TP/PDECGF activity in patients with renal cell carcinoma (RCC). The authors examined the enzymatic