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Suppression of tubulin tyrosine ligase activity through reversible phosphorylation: a mechanism for inhibition of α-tubulin tyrosinylation

✍ Scribed by H.T. Idriss


Book ID
117840086
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
88 KB
Volume
56
Category
Article
ISSN
0306-9877

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Phosphorylation of tubulin tyrosine liga
✍ Idriss, Haitham T. 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 77 KB 👁 1 views

The tubulin tyrosination/detyrosination cycle is a well-established posttranslational modification, which is carried out by two enzymes: Tubulin Tyrosine Ligase (TTL) and Tubulin Tyrosine Carboxypeptidase (TTCP). In this paper, I present evidence suggesting that the cycle itself is under the hierarc