Suppression of the TRIF-dependent signaling pathway of toll-like receptors by isoliquiritigenin in RAW264.7 macrophages
β Scribed by Se-Jeong Park; Ho-Yeon Song; Hyung-Sun Youn
- Publisher
- Korean Society for Molecular and Cellular Biology
- Year
- 2009
- Tongue
- English
- Weight
- 235 KB
- Volume
- 28
- Category
- Article
- ISSN
- 1016-8478
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Adherent pathogenβassociated molecular patterns (PAMPs) act through tollβlike receptor 2 (TLR2) and TLR4 to increase the biological activity of orthopedic wear particles in cell culture and animal models of implant loosening. This study tested whether this is dependent on TLR associatio
Secretion of urokinase-type plasminogen activator (uPA) by RAW264.7 cells was stimulated by heparin in a dose-and time-dependent manner. Secretion of uPA was not detected when cells were exposed to heparin at 4"C, indicating that heparin was not simply releasing receptor-bound uPA. Furthermore, prio