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Characterization of TRPM8-Like Channels Activated by the Cooling Agent Icilin in the Macrophage Cell Line RAW 264.7

โœ Scribed by Sheng-Nan Wu; Pei-Yu Wu; Mei-Ling Tsai

Publisher
Springer
Year
2011
Tongue
English
Weight
611 KB
Volume
241
Category
Article
ISSN
0022-2631

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Secretion of urokinase-type plasminogen activator (uPA) by RAW264.7 cells was stimulated by heparin in a dose-and time-dependent manner. Secretion of uPA was not detected when cells were exposed to heparin at 4"C, indicating that heparin was not simply releasing receptor-bound uPA. Furthermore, prio