Suppression of rheumatoid factor synthesis by antiidiotypic antibody in rheumatoid arthritis patients with cross-reactive idiotypes
β Scribed by Tsutomu Takeuchi; Osamu Hosono; Jun Koide; Mitsuo Homma; Tohru Abe
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 813 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0004-3591
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We quantified rheumatoid factor cross-reactive idiotype (RF-CRI) in whole serum from RF+ rheumatoid arthritis (RA) patients, using an inhibition enzymelinked immunosorbent assay which is not affected by the presence of IgG. Serum from 16 RF+ RA patients contained 2-252 pg/ml RF-CRI (geometric mean \
## Abstract Serum antibodies reactive with the keratin layer of rat esophagus (AKA) were found in 46 of 80 (57.5%) rheumatoid arthritis (RA) patients. In contrast, AKA were present in only 7 of 82 (9.5%) patients with other types of rheumatic disorders and in 2 of 47 (4.2%) healthy subjects. AKA we