Suppression of PMA-induced tumor cell invasion by dihydroartemisinin via inhibition of PKCα/Raf/MAPKs and NF-κB/AP-1-dependent mechanisms
✍ Scribed by Yong Pil Hwang; Hyo Jeong Yun; Hyung Gyun Kim; Eun Hee Han; Gye Won Lee; Hye Gwang Jeong
- Book ID
- 113489142
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 1012 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0006-2952
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Matrix metalloproteinase-9 (MMP-9) plays an important role in the invasion and metastasis of cancer cells. In this study, we examined the inhibitory effect of bee venom (BV) and its major peptides, melittin and apamin, on PMAinduced invasion induced by MMP-9 expression in Caki-1 renal cancer cells.
## Abstract **Scope:** Capsaicin is a cancer‐suppressing agent. The aim of our study was to determine the effect of capsaicin on tumor invasion and migration; the possible mechanisms involved in this inhibition were investigated in human fibrosarcoma cells. **Methods and results:** We employed inv