𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells

✍ Scribed by H. Wang; M. Iezzi; S. Theander; P. A. Antinozzi; B. R. Gauthier; P. A. Halban; C. B. Wollheim

Book ID
105817984
Publisher
Springer
Year
2005
Tongue
English
Weight
349 KB
Volume
48
Category
Article
ISSN
0012-186X

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

SREBP-1c, Pdx-1, and GLP-1R involved in
SREBP-1c, Pdx-1, and GLP-1R involved in palmitate–EPA regulated glucose-stimulated insulin secretion in INS-1 cells
✍ Shiying Shao; Zhelong Liu; Yan Yang; Muxun Zhang; Xuefeng Yu πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 381 KB

## Abstract Impairment of glucose‐stimulated insulin secretion (GSIS) caused by glucolipotoxicity is an essential feature in type 2 diabetes mellitus (T2DM). Palmitate and eicosapentaenoate (EPA), because of their lipotoxicity and protection effect, were found to impair or restore the GSIS in beta