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Suppression of N-nitrosobis(2-oxopropyl)amine (BOP)-induced biliary carcinogenesis in bilioenterostomized hamsters by etodolac, a selective cyclooxgenase 2 inhibitor

✍ Scribed by Noritsugu Tsuneoka; Yoshitsugu Tajima; Amane Kitazato; Kenzo Fukuda; Tomoo Kitajima; Tamotsu Kuroki; Shinya Onizuka; Takashi Kanematsu


Book ID
119241011
Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
69 KB
Volume
9
Category
Article
ISSN
1091-255X

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## Abstract The modification effects of nimesulide, a cyclooxygenase (COX)‐2 inhibitor, administration during the postinitiation phase of pancreatic carcinogenesis were investigated in hamsters treated with __N__‐nitrosobis(2‐oxopropyl)amine (BOP). Male Syrian hamsters were given 4 weekly s.c. inje