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Suppression of lectin, alloantigen, and xenoantigen-induced T-cell proliferation by Genistein

✍ Scribed by F.T. Rapaport; T. Terashima; K. Tsukuda; K. Kono; T. Takayama; K. Malinowski


Book ID
117234454
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
446 KB
Volume
29
Category
Article
ISSN
0041-1345

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## Abstract The limitation of proliferative potential in human somatic cells imposed by replicative senescence has been proposed as a mechanism of tumor suppression. The E3 ubiquitin ligase Smurf2 is up‐regulated during replicative senescence in response to telomere shortening, and induces senescen