## Abstract The lack of efficacy of available therapies for the treatment of malignant melanoma has emphasized the need to develop novel therapeutic strategies to prevent melanoma growth. We have tested whether the antiβHMWβMAA mAb 225.28S is able to inhibit human melanoma tumor growth in SCID mice
β¦ LIBER β¦
Suppression of human melanoma cell growth and metastasis by the melanoma-associated antigen CD63 (ME491)
β Scribed by Kristen J. Radford; Julia Mallesch; Peter Mersey
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- French
- Weight
- 678 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0020-7136
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We have studied the experimental metastasis of H-2+ and H-2-melanoma sublines in H-2b/b and H-Zdb hosts by enumerating pulmonary colonies 20-50 days after i.v. inoculation of tumor cells. In H-2b'b hosts, the H-2+ "616-S" cells gave rise to a moderate number of metastatic colonies (mean: 6.3 f 6). T