Lung colonization and metastasis by disseminated b16 melanoma cells: H-2 associated control at the level of the host and the tumor cell

✍ Scribed by Kazuto Taniguchi; Klas Käarre; George Klein

• Publisher: John Wiley and Sons
• Year: 1985
• Tongue: French
• Weight: 805 KB
• Volume: 36
• Category: Article
• ISSN: 0020-7136
• DOI: 10.1002/ijc.2910360415

✦ Synopsis

We have studied the experimental metastasis of H-2+ and H-2-melanoma sublines in H-2b/b and H-Zdb hosts by enumerating pulmonary colonies 20-50 days after i.v. inoculation of tumor cells. In H-2b'b hosts, the H-2+ "616-S" cells gave rise to a moderate number of metastatic colonies (mean: 6.3 f 6). The "BL16-