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Suppression of gonadotrophin secretion does not reverse premature ovarian failure

โœ Scribed by R. M. F. van der Weiden; F. M. Helmerhorst


Book ID
111154673
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
81 KB
Volume
96
Category
Article
ISSN
1470-0328

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X chromosome inactivation does not defin
โœ Marian A. Spath; Willy N. Nillesen; Arie P.T. Smits; Ton B. Feuth; Didi D.M. Bra ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 159 KB ๐Ÿ‘ 2 views

## Abstract Since only 20% of female fragile X premutation carriers develop premature ovarian failure (POF, i.e., amenorrhea before age of 40 years), and since X chromosome inactivation (XCI) determines the phenotypic severity of full mutation women, we reasoned that the development of POF in fragi