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Suppression of Experimental Autoimmune Uveitis by FTY720

✍ Scribed by Alessandra Commodaro; Juliana Pedregosa; Jean Pierre Peron; Rubens Belfort Jr; Luis Vicente Rizzo; Valquiria Bueno

Book ID
113541628
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
37 KB
Volume
135
Category
Article
ISSN
1090-2341

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## Abstract FTY720, an oral sphingosine 1‐phosphate (S1P) receptor modulator, has shown efficacy in phase II trials in patients with relapsing‐remitting multiple sclerosis (MS). Although this molecule is thought to immunosuppress by inhibiting lymphocyte egress from the lymph nodes, the full spectr