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Amelioration of Experimental Autoimmune Encephalomyelitis in Lewis Rats by FTY720 Treatment

✍ Scribed by Fujino, M.


Book ID
118161136
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2003
Tongue
English
Weight
497 KB
Volume
305
Category
Article
ISSN
0022-3565

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## Abstract FTY720, an oral sphingosine 1‐phosphate (S1P) receptor modulator, has shown efficacy in phase II trials in patients with relapsing‐remitting multiple sclerosis (MS). Although this molecule is thought to immunosuppress by inhibiting lymphocyte egress from the lymph nodes, the full spectr