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Suppression of Dicer Increases Sensitivity to Gefitinib in Human Lung Cancer Cells

โœ Scribed by Chen, Jui-Chieh; Su, Yen-Hao; Chiu, Ching-Feng; Chang, Yi-Wen; Yu, Yang-Hao; Tseng, Chi-Feng; Chen, Hsin-An; Su, Jen-Liang

Book ID
121675997
Publisher
Springer
Year
2014
Tongue
English
Weight
883 KB
Volume
21
Category
Article
ISSN
1068-9265

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## Abstract The epidermal growth factor receptor (EGFR) tyrosineโ€kinase inhibitor gefitinib (Iressaยฎ, ZD1839) has shown promising activity preclinically and clinically. Because comparative investigations of drugโ€resistant sublines with their parental cells are useful approaches to identifying the m