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Suppression of Stat3 activity sensitizes gefitinib-resistant non small cell lung cancer cells

โœ Scribed by Huan-Chih Chiu; Ding-Li Chou; Chin-Ting Huang; Wen-Hsing Lin; Tzu-Wen Lien; Kuei-Jung Yen; John T.-A. Hsu


Book ID
113489477
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
768 KB
Volume
81
Category
Article
ISSN
0006-2952

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## Abstract The epidermal growth factor receptor (EGFR) tyrosineโ€kinase inhibitor gefitinib (Iressaยฎ, ZD1839) has shown promising activity preclinically and clinically. Because comparative investigations of drugโ€resistant sublines with their parental cells are useful approaches to identifying the m