Suppression of anchorage-independent growth of human cancer cell lines by the drs gene
β Scribed by Yamashita, Atsuko; Hakura, Akira; Inoue, Hirokazu
- Book ID
- 110062266
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 693 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0950-9232
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π SIMILAR VOLUMES
We have previously observed that a human adrenal carcinoma cell line (SW-13) produces autocrine growth factors that enhance the ability of these cells to clone in soft agar. We now show that a basic FGF-like protein is found in SW-13 lysates and stimulates SW-I3 colony growth. Basic FGF (bFGF) was i
## Abstract Immortal, nontumorigenic cell lines of Syrian hamster embryo (SHE) cells with different tumorβsuppressing activity were isolated. Subclones from the parental cells were isolated that either had retained (supB^+^) or lost (supB^β^) the ability to suppress tumorigenicity after hybridizati