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Suppression by nimesulide of bombesin-enhanced peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats

✍ Scribed by Hiroyasu Iishi; Masaharu Tatsuta; Miyako Baba; Hiroyuki Yano; Koji Higashino; Mutsuko Mukai; Hitoshi Akedo


Book ID
111554474
Publisher
Springer
Year
2003
Tongue
English
Weight
92 KB
Volume
20
Category
Article
ISSN
0262-0898

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Genistein attenuates peritoneal metastas
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The effects of the soybean isoflavonoid genistein on the development of bombesin-enhanced peritoneal metastasis from intestinal adenocarcinomas induced by azoxymethane (AOM) were investigated in male inbred Wistar rats. From the beginning of the experiment, rats were given 10 weekly s.c. injections

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## Abstract The effect of cyclic phosphatidic acid, a unique analogue of lysophosphatidic acid, on the induction of bombesin‐enhanced peritoneal metastases from intestinal adenocarcinomas induced by azoxymethane was investigated in male Wistar rats. Rats were given 10 weekly injections of azoxymeth