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Support for the N -Methyl-D-Aspartate Receptor Hypofunction Hypothesis of Schizophrenia From Exome Sequencing in Multiplex Families

✍ Scribed by Timms, Andrew E.; Dorschner, Michael O.; Wechsler, Jeremy; Choi, Kyu Yeong; Kirkwood, Robert; Girirajan, Santhosh; Baker, Carl; Eichler, Evan E.; Korvatska, Olena; Roche, Katherine W.; Horwitz, Marshall S.; Tsuang, Debby W.


Book ID
120226520
Publisher
American Medical Association
Year
2013
Tongue
English
Weight
413 KB
Volume
70
Category
Article
ISSN
2168-622X

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Glutamate-activated ionic currents in cu
✍ T. Clasen; G. Jeserich; T. KrΓΌppel πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 782 KB

Glutamate-induced currents were recorded from cultured trout astrocytes with the whole-cell variation of the patch-clamp technique. Ninety percent of the tested cells were directly depolarized by the amino acid neurotransmitter in a concentration-dependent manner. The depolarizing effect was due to