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superoxide dismutase-like immunoreactivity in Lewy body-like inclusions of sporadic amyotrophic lateral sclerosis

✍ Scribed by Shibata, Noriyuki; Hirano, Asao; Kobayashi, Makio; Sasaki, Shoichi; Takeo, Kato; Matsumoto, Sadayuki; Shiozawa, Zenji; Komori, Takashi; Ikemoto, Akito; Umahara, Takahiko


Book ID
122645021
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
590 KB
Volume
179
Category
Article
ISSN
0304-3940

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## Abstract Mutant superoxide dismutases type 1 (SOD1s) cause amyotrophic lateral sclerosis by an unidentified toxic property. In a patient carrying the G127X truncation mutation, minute amounts of SOD1 were found in ventral horns using a mutant‐specific antibody. Still, both absolute levels and ra