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Superoxide dismutase-1 and other proteins in inclusions from transgenic amyotrophic lateral sclerosis model mice

✍ Scribed by Daniel Bergemalm; Karin Forsberg; Vaibhav Srivastava; Karin S. Graffmo; Peter M. Andersen; Thomas Brännström; Gunnar Wingsle; Stefan L. Marklund


Book ID
111184014
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
500 KB
Volume
114
Category
Article
ISSN
0022-3042

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## Abstract High molecular weight detergent‐insoluble complexes of superoxide dismutase 1 (SOD1) enzyme are a biochemical abnormality associated with mutant SOD1‐linked familial amyotrophic lateral sclerosis (FALS). In the present study, SOD1 protein from spinal cords of transgenic FALS mice was fr