Superinfection by Epstein-Barr virus of a subset of Raji cells is independent of HLA class-II antigens
β Scribed by Alberto Faggioni; Claudia Zompetta; Mara Cirone; Giuseppe Barile; Luigi Frati; Roberto Accolla
- Book ID
- 102276832
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- French
- Weight
- 95 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0020-7136
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## Abstract In an attempt to qualitatively identify the membrane antigen (MA) complex induced by EpsteinβBarr virus (EBV) infection of lymphoblastoid cells, superinfected Raji cells were surface labelled with ^125^I by the lactoperoxidase method and solubilized with Triton Xβ100, then the ^125^(βla
## Abstract Biochemical properties of EpsteinβBarr virus (EBV)βrelated soluble antigen in nonβproducer Raji Burkitt lymphoblastoid cells, assayed by the indirect single radial immunodiffusion (ISRD) test, were investigated. The soluble ISRD antigen retained activity even after exposure to a tempera
We have shown that modulation of intracellular calcium in EBV latently infected cells could induce the expression of viral antigens, and suggested that a protein kinase-C (PKC) may play a major role in the EBV genome activation. We now report further investigations on the role of PKC using 2 selecti