Fluorescence in situ hybridization (FISH) using chromosome-specific plasmid libraries and chromosome region-specific DNA markers allowed the characterization of a t( 1022; I I ) (p I I .2;q I2;q24) in a Ewing's sarcoma (ES). This study illustrates the usefulness of molecular cytogenetic analysis of
✦ LIBER ✦
Superficial primitive Ewing's sarcoma: a clinicopathologic and molecular cytogenetic analysis of 14 cases
✍ Scribed by Terrier-Lacombe, Marie J; Guillou, Louis; Chibon, Frédéric; Gallagher, Gabrielle; Benhattar, Jean; Terrier, Philippe; Ranchère, Dominique; Coindre, Jean-Michel
- Book ID
- 109887582
- Publisher
- Nature Publishing Group
- Year
- 2008
- Tongue
- English
- Weight
- 302 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0893-3952
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Polymerase chain reaction (PCR)-directed sequence analysis was performed to characterize the genomic and cDNA breakpoint junctions of t( I I ;22) (q24;q 12) translocation in a case of Ewing's sarcoma, in which the EWS gene located on chromosome 22 is rearranged with the FUI gene located on chromosom