achievable with capillary gas chromatography to be Capillary supercritical fluid chromatography and its combination with mass spectrometry (SFC-MS) is an important analytical methodology for the analysis of thermally labile and high molecular weight compounds. The mass spectrometer provides sensitiv
Supercritical fluid chromatography - mass spectrometry
โ Scribed by R.D. Smith; J. Fjeldsted; M.L. Lee
- Publisher
- Elsevier Science
- Year
- 1983
- Weight
- 284 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0020-7381
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## Abstract Chromatography with a supercritical fluid as the mobile phase was suggested more than four decades ago (Klesper, E., Corwin, A. H., Turner, D. A., __J. Org. Chem__. 1962, __27__, 700โ701). Supercritical fluid chromatography (SFC) is basically a hybrid of GC and LC that eases the resolut
A benchtop SFCIMS system is described which utilizes supercritical carbon dioxide in a 50 micron diameter open tubular column interfaced directly to an unchanged commercially available benchtop capillary GCIMS system equipped with a chemical ionization (Cl) source. A small amount of methane reagent