✍ Scribed by Bob W. Wright; Harold R. Udseth; Richard D. Smith; Robert N. Hazlett
No coin nor oath required. For personal study only.
The application of capillary column supercritical fluid chromatography (SFC) and supercritical fluid chromatography-mass spectrometry (SFC-MS) to the analysis of the polycyclic aromatic hydrocarbon fraction of selected marine diesel fuel samples is described. The chromatographic separation methods utilized pressure or density programming techniques and small diameter (50 pm) capillary columns. This work demonstrates the feasibility of achieving high-resolution separations of medium polarity compounds using nonpolar carbon dioxide as the mobile phase in SFC and the successful coupling of SFC to MS to obtain mass chromatograms and reliable chemical ionization mass spectra. High resolution separations of the polycyclic aromatic hydrocarbon fractions of marine diesel fuel samples were combined with isobutane chemical ionization MS. Analysis of the more polar components will require a more polar supercritical fluid mobile phase.
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achievable with capillary gas chromatography to be Capillary supercritical fluid chromatography and its combination with mass spectrometry (SFC-MS) is an important analytical methodology for the analysis of thermally labile and high molecular weight compounds. The mass spectrometer provides sensitiv
## Abstract Chromatography with a supercritical fluid as the mobile phase was suggested more than four decades ago (Klesper, E., Corwin, A. H., Turner, D. A., __J. Org. Chem__. 1962, __27__, 700–701). Supercritical fluid chromatography (SFC) is basically a hybrid of GC and LC that eases the resolut