Superantigens

✍ Scribed by Talal Chatila; Raif S. Geha

• Publisher: Elsevier Science
• Year: 1992
• Tongue: English
• Weight: 664 KB
• Volume: 4
• Category: Article
• ISSN: 0952-7915
• DOI: 10.1016/0952-7915(92)90129-3

✦ Synopsis

Over the past three years superantigens have come to the forefront of immunological research. Studies in a number of laboratories have indicated that superantigens play a central role in shaping the T-cell repertoire in the development of tolerance, autoimmunity and immunodeficiency. This is in addition to their classic role in the pathogenesis of a number of infectious diseases.