Superantigens in disease
โ Scribed by MacDonald, H. Robson
- Publisher
- Springer
- Year
- 1996
- Tongue
- English
- Weight
- 105 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0344-4325
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Increasing evidence suggests that bacterial and viral superantigens are involved in immune-mediated disease. Studies using an animal model for multiple sclerosis show that superantigens can induce relapses and bring into play autoreactive T cells with restricted usage of T cell receptor V beta famil
Over the past three years superantigens have come to the forefront of immunological research. Studies in a number of laboratories have indicated that superantigens play a central role in shaping the T-cell repertoire in the development of tolerance, autoimmunity and immunodeficiency. This is in addi
## Abstract Superantigens secreted by the bacterial pathogen __Staphyloccocus aureus__ are extremely potent toxins that overstimulate the host immune system by binding to the MHC class II and T cell receptors and activating a large population of T cells. Superantigen infection has been shown to be