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Sulphate conjugation of biologically active monoamines and their metabolites by human platelet phenolsulphotransferase

โœ Scribed by Glen Rein; Vivette Glover; Merton Sandler


Book ID
115823491
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
720 KB
Volume
111
Category
Article
ISSN
0009-8981

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The four stereoisomers of the parent keto acid of the oximino drug ximoprofen have been prepared in high enantiomeric purity. The stereochemistry in the propionic acid chain was established by the combination of Sharpless epoxidation followed by stereoselective hydrogenolysis of the benzylic carbon-