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Sulindac resistant adenomas in familial adenomatous polyposis patients: A molecular evaluation

✍ Scribed by Keller, Josbert J.; Offerhaus, Johan A.; Drillenburg, Paul; Caspers, Eric; Musler, Alex


Book ID
124130637
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
194 KB
Volume
120
Category
Article
ISSN
0016-5085

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Familial adenomatous polyposis (FAP) represents a human model of the adenomasarcinoma sequence. Colectomy substantially reduces the cancer risk. Restorative proctocolectomy maintains continence and abolishes the risk of rectal cancer, but there is a price to pay in terms of an increased morbidity ra