Sulfur mustard induces the formation of keratin aggregates in human epidermal keratinocytes☆
✍ Scribed by James F Dillman III; Kriston L McGary; John J Schlager
- Book ID
- 113923161
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 284 KB
- Volume
- 193
- Category
- Article
- ISSN
- 0041-008X
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## Abstract We compared the effects of overexpressing a tightly regulated anti‐inflammatory cytokine, interleukin 10 (IL‐10), and the pro‐inflammatory cytokine tumor necrosis factor‐alpha (TNF‐α) on sulfur mustard induced cytotoxicity in human epidermal keratinocytes. Both cytokines were overexpres
This study examines the transcriptional response of human epidermal keratinocytes (HEK) to sulfur mustard (HD) in order to gain a better understanding of the intracellular events that result in cytotoxicity. Differential display polymerase chain reaction technology was used to examine the relative t