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Quantification of sulfur mustard-induced DNA interstrand cross-links and single-strand breaks in cultured human epidermal keratinocytes

✍ Scribed by Mol, Marijke A.E.; van der Schans, Govert P.; H.M. Lohman, Paul


Book ID
121272688
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
827 KB
Volume
294
Category
Article
ISSN
0921-8777

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2-Acetylaminofluorene (AAF) or trans-4-acetylaminostilbene (AAS) was orally or intraperitoneally administered to female Wistar rats. DNA from liver cells was analyzed for single-strand breaks by the alkaline elution assay. Only borderline effects were observed with doses (100 pmol/kg) used in animal