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Sulfur-containing derivatives of β-phenethylamine: Methanesulfonamides

✍ Scribed by William O. Foye; Jon C. Anderson; Jayant N. Sane

Publisher
John Wiley and Sons
Year
1971
Tongue
English
Weight
253 KB
Volume
60
Category
Article
ISSN
0022-3549

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✦ Synopsis

N-Methanesulfonyl derivatives of j3-phenethylamine, (+)-amphetamine, j3-4-aminophenethylamine, and 4-(2-trifluoro-acetamidoethy1)aniline have been prepared. N-Trifluoroacetyl-1-(4- rnethanesulfonamidophenyl)-2-ethylamine significantly lowered blood pressure in hypertensive rats, and the methanesulfonamide of (+)-amphetamine lowered blood pressure in the dog.

Keyphrases 0 Methanesulfonamides-synthesis, pharmacological screening as antihypertensives I J 8-Phenethylamine, sulfur-containing derivatives-synthesis, pharmacological evaluation 0 Antihypertensive agents, potential-synthesis, evaluation of Nrnethanesulfonyl derivatives of 8-phenethylamine

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